After a car wreck on the winding Mulholland Drive renders a woman amnesiac, she and a perky Hollywood-hopeful search for clues and answers across Los Angeles in a twisting venture beyond dreams and reality. David Lynch took the remnants of his failed television pilot, reworked it and added newly shot material to create one of the defining films of his career, making a star of Naomi Watts in the process, with Laura Haring and Justin Theroux co-starring.